I rented a U-Haul MC trailer to go 100 miles to pick up my Feejer when I bought it. Their trailer has a lousy ramp design, although it's cheap; the ramp just stands up vertically like all those yard-man trailers you see carrying mowers around. Towed it behind an '89 Mercury Grand Marquis, and it was horrible to tow empty, with that ramp standing up in the back like a parachute. I could only get the rig up to 55, and the car's trip computer was in single-digit MPG readouts then, usually high 20s low 30s at 55. With the bike on it I had a much better drive, was able to hold 60 showing about 15 to 18 MPG on the computer. I guess the bike streamlined it.
No trouble with the trailer or with U-haul, and I brought it back the following day, but less than 24 hours, so it was only 1 day's rental. Also, their insurance was pretty cheap (less than 10 bucks, I think) and covers not just their trailer but whatever's on it. Since I'd just bought the bike and not insured it yet, I went that way, just for peace of mind.
With that distance, I'd look into a 1-way rental. The gas mileage difference on the tow vehicle, especially dragging that sail all the way back, might make up the price difference.