I've got a '04 Wee and a '13 FJR...the Wee is a fantastic bike, and I use it as my daily commuter. The vibes on the WeeStrom are not bad at all (nothing like a 40-50 degree V-twin such as on most cruisers). I've taken it on a couple of longish cruises....while very comfortable and capable, it is not as good as the FJR for higher mileage...but anything less than about 200 miles, no problem. I have a Sargent seat on both my bikes, and I believe the seat is a great match for the Wee, as well as the FJR.
If I could only have one bike, I'd want it to be the FJR, but if forced to keep only the Wee, I'd probably be ok with it. If you are not doing mega mileage, you will probably be ok with it also.