I will be heading out there from the western slope. Right now plans are to go to WFO in Idaho first, then make way to Monterey from the north. If WFO gets cancelled I might explore other routes.
My traditional route from here is down to Flagstaff, across 40 to Laughlin (cheap overnight to break up the HOT desert), across 58 to Bakersfield and then 58 to the coast and up Hwy 1. I still have not heard about the progress of the slide on HWY 1 but this route may not be possible.
I have done 50 across Nevada (expensive fuel in some locations) but once you get to Tahoe there are lots of options through the sierras. I prefer 88 because of light traffic, good road conditions (last time I rode it) and great scenery. Options are also there to hit 49 south before making your way west on 140 to 152.
What kind of tickets do you have for the MotoGP. I would encourage anyone to do one of the hospitality package deals. Flagroom at turn 4-5 or any of the others are well worth it IMHO. Most include parking and the food and beer has been good out there. If you dont go for one of these, the Parade lap ticket includes MC parking in a prime location and is a great deal for just the parking.