Absolutely true that it is no guarantee that you will get the best additive package all the time but buying premium from the majors stacks the deck in your favor. There have been several situations over the past years that I was involved with where problems cropped up with particular brands of fuel in certain areas that also tends to support the idea that the majors put a better additive package in premium.
In any area all the gasoline likely comes from the same terminal anyway.....so the gasoline itself is the same. The only difference is the additive package in the fuel and the improved quality assurance from the majors that you are not buying a load of alcohol in the fuel.
There are many factors that affect the power output of an engine on a dyno. Even the volitility of the fuel can affect atomization and fuel distribution and HP....and that has nothing to do with octane rating. I've seen numerous dyno tests on some pretty sophisticated dynos trying to "prove" that regular makes more power than premium....only to prove that it doesn't matter.
Weed eaters work great at about 40:1 on Citgo Sea and Snow two stroke oil premixed. The Citgo Sea and Snow two stroke oil is one of the better products on the market and is actually one of the less expensive. We go thru gallons of the stuff in the winter in sleds and it works excellently. No reason to go leaner on oil as many studies prove that the more oil the better for HP basically. Just remember that if the carb is running premix then changing the premix ratio will change the A/F ratio the engine is running at (oil replaces gasoline in the jet so more oil equals less fuel and a leaner mixture) so you have to set the carb up on the premix ratio and stick with it. Believe it or not.....I have done some "research" on this with mod'ed weedeater engines....LOL. You should hear my leaf blower run. It is the envy of the neighborhood.
I couldn't agree more that it pays to by gas from the majors. In another life I worked at a refinery and I screwed up my share of gas and oil and believe me, there's a thriving market for low priced off spec product. The majors don't sell it at their own stations but they damn sure sell it. We had a guy who specialized in selling it and the Habib's type gas & liquor stores line up to buy it. Even now in my current incarnation I just sold 25,000 gallons of 10 year old #2 diesel fuel to a major distributor (not a refiner) who just blended it in with their stock. Buyer beware.