Or if you're a real dork, your mileage spreadsheet (updated at every fillup) also tracks the miles on the F-tripmeter. When you fill up, you can not only calculate the overall mpg, you can also calculate the miles before the F-turned on, and back out how many gallonws are left when the F comes on, if you assume the published capacity is accurate, which is a bit of a gamble. Usually the tank holds a bit more.
So, if you're a risk-taker like me, you push it farther and farther, especially when you're in a place where you could call for help or push to the station. For my '06 Gen II, I have determined that the main fuel capacity (before the F starts flashing) is 5.04 gal (std deviation of 0.08 gal) and I have gotten as much as 67 miles and 1.6 gal out of the bike after hitting the F, although on that tank, it died a few times and stumbled into the station! But several times greater than 1.3 gal calculated after hitting F flashing. (Note that 1.3 is the nominal "reserve capacity" as well.)
So, my typical mileage is about 43 mpg, so I figure I'm good for 56 miles no problem after the F starts flashing.