Life's not safe. Anyone who claims otherwise hasn't thought it through or is trying to sell you something.
No one gets out of here alive.
The lack of 4 wheels means that the rider is burdened with the safety. As with firearms, mechanical safeties are seldome 100%. The only safety we can count on is between our ears. That means a rider tosses a leg over the bike KNOWING the risks (and managing them accordingly) or is a clueless organ donar. This understanding has to be "owned" and that means not over riding you site line on the street, performing PM at or before the designated intervals, inspecting tires and replacing them based on anticipated use ((early if required for an upcoming trip). Penny pinching on maintenance can cost you more than it's worth in the end.
Heading out with poorly maintaned equipment
Pushing hard on public roads
Too fast to avoid unexpected obstacles or debris
All of these are personal choices that are part of managing risk. Push too much and the world pushes back. It's not brain surgery. The trouble is that many people don't like staring their mortality in the face, so gloss over it.
That doesn't mean we lay the blame on the equipment and start looking for redundant systems (4 wheels don't tip over, so add 2 to your bike). It means the intellectually honest rider acknowleges the risks and adjusts their riding accordingly. At some point where something happens, they look into themselves to learn how to alter their habits to prevent it from happening again.