I love my PR2s, but agree with the comments about the last third or so of tire life, particularly the front. It becomes triangulated, then handles like ****. Comes off vertical just fine, then wants to stay on its now-flattish surface. If you need to tighten your line and lean more when the tire is in these last few hundred miles of life, good luck. Pull harder on the handlebars and use your body to get it off that surface, and then it wants to go over that edge, and feels like it will fall on its side. I'm not Miguel Duhamel, and don't have his level of skill that allowed him to ride on the edge of the tire; your skill set may differ.
Anyway, 3,000 miles on a set. Sometimes 2,800, sometimes 3,200. I am very attentive to tire pressure; 42 psi front and rear. Don't know what I'm going to do when PR2s disappear. They are getting harder to find.