Would indexing the plugs have any beneficial effect to adding power or reducing potential to detonation? You often hear the engine tuners mention indexing the plugs to present the incoming fuel charge the most direct exposure to the spark. Also would the position of the electrode be better served by indexing to maximize the cooling off during the end of the power stroke and during the exhaust stroke?
In some very highly tuned engines indexing the plugs might provide a tiny bit of power....but I think the effect is un-measureable in most cases. It wouldn't have any noticeable effect on detonation. The indexing is usually most effective in situations where there is extreme in-cylinder mixture motion such that the motion trys to quench or blow out the spark. Indexing can "protect" the initiating flame kernal and help with more stable combustion.
I have seen studies on indexing plugs on a variety of different combustion chambers from production engines and it showed absolutely no gain in those cases. By the same token, there have been dyno comparisons with spark plugs with multiple ground electrodes (the infamous Bosch Plus 4 plugs) and they were shown to reduce power a bit. Not a lot but measureable and repeatable. The thought is that the redundant ground electrodes tend to shield or impede the initiating flame front and/or quench it to some extent due to the multiple heat sinks to soak up the heat. Not the sort of result you would expect from the marketing for those plugs!!
In many pure competition engines, especially drag race engines with very high compression ratios, the spark plug ground electrode can come pretty close to the piston dome at TDC. Some engines like this need to have the plugs "indexed" to keep the ground electrode to the one side or the other so that it does not hit the piston. This problem may be confused with indexing for more power.
The eletrode that needs "cooling" is the center electrode, not the ground electrode that would be indexed. Unless the ground electrode were somehow shielding or acting as a wind break to prevent the center electrode from the mixture it really will not affect the heat range of the center electrode or how hot it runs. The center electrode cools by rejecting heat to the shell of the spark plug so the projection of the center electrode and the length of the porcelean is what governs heat range, not the position of the ground electrode.
There can be an issue with cooling of the ground electrode itself, especially with very high compression, highly turbocharged engines and engines running nitrous oxide. Most tuners in those situations know to clip the ground electrode to shorten it considerably to improve the cooling and reduce the extension of the ground electrode away from the shell.
In any case, concerns about indexing and the center and ground electrode cooling would affect pre-ignition, not detonation.