Just curious, why ride on such a dangerous weekend as Memorial Day. Way too much traffic and motorist for me.
I won't ride congested roads (or ski crowded resorts) on holiday weekends. So, I won't ride near a city at those times, or someplace like Lake Tahoe, Yosemite, Napa Valley, Lake Berryessa or on the way to any of them. Knowing the situation in Fremont getting out of town on such a weekend (or back in), I understand why you asked.
But that's where a little local mountain roads knowledge comes in. A couple years ago, I did this ride on July 4, 5 and 6, which was a 3 day weekend. Almost nobody on most of it, and Yreka was deserted. We didn't have motel reservations for Saturday night in Yreka or Sunday night in Fortuna -- no problem. 96 has nearly no one on it, and even then, it's mostly motorcycles. 89 north of Graeagle is mostly sparse traffic. I only ride such weekends out in the boonies where the most common mass vacation destinations aren't up ahead. Keep in mind that even if someone is going to Lake Almanor (for example), they are typically going to try to arrive Friday night and then go boating or golfing. Tahoe is an excellent contrasting example, however: the motoring touristas are all sightseeing around the lake and not paying attention.
In the more remote areas I'm suggesting, most of those recreating on the roads are us motorcyclists.